AFM BIO

General information

Category

Microscopy

Key instrumentation
AFM/SPM

The instrument allows topological images of biological samples, e.g. tissues and cells. It can be used as a nano-manipulation instrument, allowing modifications of the morphology of a substrate. For biological systems, it also allows the nano-stimulation of the sample. The instrument features an XY-stage with a transmission optical microscope, allowing the acquisition of images in time laps during cell culture.

Technical description
The instrument allows to characterise of a maximum lateral dimension of 100 µm x 100 µm, a maximum height of 10 µm, and it is equipped with a cantilever holder for conductometry measurements. The optical microscope features magnification factors of 5x, 10x, 20x, 40x and maximum movements in the XY stage of 10 mm x 10 mm. Operational modes include non-contact mode, solid/liquid contact mode, solid/liquid tapping mode, solid/liquid with force spectroscopy; (Solid/Liquid) Nanolithography; Nano-Kelvin probe; and conductive-enhanced AFM.
Research areas and applications

Topographical analysis pf solid substrates and biological samples in liquid, nanolithography of rigid substrates, nanostimulation of cells.

Science highlights

Experimental team

Instrument Scientist
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